Challenge 22

Charlie’s Challenge series was officially launched during the pandemic in 2021 and was called Challenge 21. You can find out about how this started off the back of the Covid-19 pandemic here. Challenge 21 created a multitude of tasks, ideas and challenges to help motivate, support and fundraise and they were all centred around the number 21.

We’re thrilled to say that in 2022 we’re continuing with this fantastic campaign with Challenge 22.

We’re looking for people who want to help, who want to get fit, who want to try something different, who want to achieve something, who want to raise funds – whether collectively or individually – and we’re looking for people who want to make a real difference to those who suffer from the incurable and life-limiting condition that is mitochondrial disease. And the question on our lips is: what will you do?

What is Challenge 22?

Challenge 22 is a collection of 22 challenges, and we’ve got something for everyone: runners, swimmers, riders, bakers, readers, entertainers, gamers, active people, quiet people, ambitious people, busy people, team challenges and individual challenges too, so no matter your abilities, time or skills, we’ve got you covered. Just take a look at our challenges below for all the inspiration you need to get involved in fundraising for our wonderful charity.

We’ll be looking for participants to sign up for each challenge and depending on the challenge we’ll be looking for people to raise £22, £220, £2200 or be a part of raising £22,000!

We have a whole host of ways in which you can support us from collecting pennies at home to baking cakes, to abseiling and cycling, to horse riding and reading, to shopping at your favourite online stores, to knitting and crafting – there is something for everyone. Our Challenge 22 campaign launches in during Volunteers’ Week in June 2022 and will run until December 31st 2022 so you have plenty of time to get your fundraising activities planned, started and achieved!

Why support us?

Every day a child in the UK will be born and go on to be diagnosed with a mitochondrial disorder. There’s currently no cure for this debilitating disease, and very few treatments, and most children that live with mitochondrial disease won’t live to see their fifth birthday. This is a truly haunting statistic – and one that we wish to change through funding pioneering research – but we also want to give sufferers hope and support in the here and now as well as giving hope to one day finding a cure for this devastating disease.

Everything we do here at the Charlie Gard Foundation is about giving families lasting memories, and ensuring that those that live with mitochondrial disease live a fulfilling, comfortable and dignified life through the gifting of essential medical equipment, memory making gifts, garden renovations, treatment grants, family photoshoots, holidays and breaks and much more.

Your support would not only be helping us to spread awareness for the foundation, but you’ll be helping to fund vital research into better treatments, and funding precious memories for families that don’t have the luxury of time with their loved ones. We can’t give the gift of time, but we can help our families make the most of every precious moment they have, and by gifting us your time and support you’ll be making a difference to hundreds of families and individuals around the UK, and helping us to create a brighter mito future because mito matters.

How do I sign up?

You can view all of our challenges underneath our video below. On each page there is a sign-up form so please do have a good browse of the challenges and then sign up for what you’d most like to do. Fancy more than one challenge? No problem! Each form asks which challenge you’d like to do so simply mention them in the comments and we’ll be in touch with you about the next steps! And for any queries or questions please don’t hesitate to email Stephanie at

What will you do?

Challenge 22

Challenge One – Money Boxes

We’re looking for people to receive one of our money boxes. Could you raise vital funds through loose change? More information.


Challenge Two – Sponsored Read

We’re looking for children to take part in a sponsored read. Could you raise vital funds by reading your favourite books? More information.

Challenge Three – Facebook Fundraiser

We’re looking for people to set up a Facebook fundraiser for us. Could you raise funds via social media? More information.

Challenge Four – Online Shopping

We’re looking for people to sign up to one of our shopping platforms. Could you raise funds whilst shopping? More details.

Challenge Five – Baking!

We’re looking for people to ‘raise’ vital funds through their love of cakes! Could you bake for us? More information.

Challenge Six – Business Support

We’re looking for businesses to pledge to raise either £2, £220 or £2200! Could your business be up for the task? More information.

Challenge Seven – Dress Up/Down Day

We’re looking for 22 organisations to host a dress down/up day at work or school. More information.

Challenge Eight – Regular Giving

We’re looking for people to support us on a regular basis, whether monthly giving or joining our lottery. More details.

Challenge Nine – Hike or Bike

We’re looking for people to raise funds by either hiking or biking – individually or collectively – 22 miles! More details.

Challenge Ten – Arts and Crafts

We’re looking for 22 people to raise vital funds through arts and crafts. Could you craft for us? More information.


Challenge Eleven – Charlie's Cheeky Monkey Run

We’re looking for children, schools, children’s centres or nurseries to take on a Cheeky Monkey Run! More details.

Challenge Twelve – Race for Charlie

This is our Challenge 22 wild card! Could you run a half marathon either virtual or physical? More information.

Challenge Thirteen – Gaming!

We’re looking for 22 people to raise vital funds through their love of gaming! Could you accept the challenge? More details.

Challenge Fourteen – Escape Room!

We’re looking for people to raise vital funds by simply having fun! Could you host a virtual escape room? More information.

Challenge Fifteen – Raffles!

We’re looking for people to host a ten-prize raffle to raise funds! Could you host a raffle? More information.

Challenge Sixteen - Club Time!

We’re looking for clubs to create some fun, inventive and collective fundraising events. More information.

Challenge Seventeen – Dog Walking!

We’re looking for fabulous doggies to participate in a sponsored walk. Could your dog walk for mito? More information.

Challenge Eighteen - Sky Diving

We’re looking for people who could take on a once-in-a-lifetime skydive for charity! Could this be you? More information.

Challenge Nineteen - Thrill Seekers!

We’re looking for thrill seekers who could tackle the great heights of London and Brighton! Are you brave enough? More details. 

Challenge Twenty – Land's End to John O' Groats

We’re looking for people to raise vital funds to collectively walk 874 miles from Land’s End to John O’ Groats. More details.

Challenge Twenty-One – Superheroes!

We’re looking for amazing superheroes to raise £1000. Could you be one of our superheroes? More details.

Challenge Twenty-Two – Volunteers

We’re looking for amazing volunteers across the UK to help support our charity. Could you volunteer for us?

Subscribe to our mailing list

  • This field is for validation purposes and should be left unchanged.